Adipose Tissue Extracellular Matrix and Vascular Abnormalities in Obesity and Insulin Resistance
نویسندگان
چکیده
منابع مشابه
Adipose extracellular matrix remodelling in obesity and insulin resistance.
The extracellular matrix (ECM) of adipose tissues undergoes constant remodelling to allow adipocytes and their precursor cells to change cell shape and function in adaptation to nutritional cues. Abnormal accumulation of ECM components and their modifiers in adipose tissues has been recently demonstrated to cause obesity-associated insulin resistance, a hallmark of type 2 diabetes. Integrins an...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2011
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2011-1567